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This target displays homology in the following species: Cow: 79%; Guinea Pig: 79%; Horse: 79%; Human: 100%; Mouse: 79%; Rat: 83%
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 39S ribosomal protein L43, mitochondrial; L43mt; Large ribosomal subunit protein mL43; Mitochondrial ribosomal protein bMRP36a
基因别名: bMRP36a; L43mt; MRP-L43; MRPL43
UniProt ID: (Human) Q8N983
Entrez Gene ID: (Human) 84545
分子生物学功能:
ribosomal protein
translational protein