Immunogen sequence: ALNLDRIRHW IGCGAHLSKP MEKLLGLAGF FPLHPMMITN AERLRRKRAR EVLLASQKTD AEATDT
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 88%.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S16P family. The encoded protein is one of the most highly conserved ribosomal proteins between mammalian and yeast mitochondria. Three pseudogenes (located at 8q21. 3, 20q13. 32, 22q12-q13. 1) for this gene have been described.
蛋白别名: 28S ribosomal protein S16, mitochondrial; Mitochondrial small ribosomal subunit protein bS16m; MRP-S16; S16mt
基因别名: CGI-132; COXPD2; MRP-S16; MRPS16; RPMS16
UniProt ID: (Human) Q9Y3D3
Entrez Gene ID: (Human) 51021
分子生物学功能: ribosomal protein