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Immunogen sequence: IFEPHVAVRD AAKMNIPTVG IVDTNCNPCL ITYPVPGNDD SPLAVHLYCR LFQTAITRAK EKRQQVEALY RLQGQKEPGD QGPAHPPGAD
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 70%.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. Alternatively spliced transcript variants have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 28S ribosomal protein S2, mitochondrial; MRP-S2; Small ribosomal subunit protein uS2m
基因别名: CGI-91; MRP-S2; MRPS2; S2mt
UniProt ID: (Human) Q9Y399
Entrez Gene ID: (Human) 51116
分子生物学功能: ribosomal protein