Invitrogen

MRPS21 Polyclonal Antibody

产品信息

PA5-50055

应用	建议稀释比	已发表文章
免疫印迹 (WB)	1:500-1:3,000	-
免疫组化（石蜡） (IHC (P))	1:50-1:100	-
免疫细胞化学 (ICC/IF)	1:100-1:500	-

产品规格
种属反应	Human, Mouse, Rat
宿主/亚型	Rabbit / IgG
分类	Polyclonal
类型	Antibody
抗原	Synthesized peptide derived from internal of human MRPS21. 查看免疫原
偶联物	Unconjugated
形式	Liquid
浓度	1 mg/mL
纯化类型	Antigen affinity chromatography
保存液	PBS, pH 7.4, with 50% glycerol
内含物	0.02% sodium azide
保存条件	-20°C
RRID	AB_2635508

产品详细信息

The antibody detects endogenous levels of total MRPS21 protein.

靶标信息

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice variants that differ in the 5' UTR; both transcripts encode the same protein.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: 28S ribosomal protein S21, mitochondrial; mitochondrial 28S ribosomal protein S21; Mitochondrial small ribosomal subunit protein bS21m; MRP-S21; S21mt

基因别名: 1810031B19Rik; MDS016; MRP-S21; MRPS21; RPMS21

UniProt ID: (Human) P82921, (Mouse) P58059

Entrez Gene ID: (Human) 54460, (Mouse) 66292, (Rat) 689432

分子生物学功能: ribosomal protein