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应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1:500-1:3,000 | - |
免疫细胞化学 (ICC/IF) |
1:100-1:500 | - |
产品规格 | |
---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthesized peptide derived from internal of human MRPS22. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2635509 |
The antibody detects endogenous levels of total MRPS22 protein.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 28S ribosomal protein S22, mitochondrial; Mitochondrial small ribosomal subunit protein mS22; MRP-S22; S22mt
基因别名: C3orf5; COXPD5; GIBT; GK002; MRP-S22; MRPS22; RPMS22
UniProt ID: (Human) P82650
Entrez Gene ID: (Human) 56945
分子生物学功能:
ribosomal protein