Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫组化(石蜡) (IHC (P)) |
1:50-1:100 | - |
产品规格 | |
---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthesized peptide derived from internal of human MRPS5. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2635514 |
The antibody detects endogenous levels of total MRPS5 protein.
Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-S5 (mitochondrial ribosomal protein S5), alternatively known as S5mt, is a 430 amino acid mitochondrial protein belonging to the ribosomal protein S5P family. A component of the 28S subunit, MRP-S5 contains one S5 DRBM domain and exists as two alternatively spliced isoforms. The gene encoding MRP-S5 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstrom syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 28S ribosomal protein S5, mitochondrial; mitochondrial 28S ribosomal protein S5; Mitochondrial small ribosomal subunit protein uS5m; MRP-S5
基因别名: MRP-S5; MRPS5; S5mt
UniProt ID: (Human) P82675
Entrez Gene ID: (Human) 64969
分子生物学功能:
ribosomal protein