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Peptide sequence: SCHMPLTGYE VWLGTLFQNP QHGEPSLQRV PVAKMVCGPS GSQLVLLKLE
Sequence homology: Cow: 77%; Dog: 85%; Horse: 85%; Human: 100%; Pig: 86%; Rabbit: 86%
MSP (or MST1) contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
Protein Aliases: Hepatocyte growth factor-like protein; Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain; hepatocyte growth factor-like protein homolog; macrophage stimulating 1 (hepatocyte growth factor-like); Macrophage stimulatory protein; Macrophage-stimulating protein; MSP
Gene Aliases: D3F15S2; DNF15S2; HGFL; MSP; MST1; NF15S2
UniProt ID: (Human) P26927
Entrez Gene ID: (Human) 4485
Molecular Function:
serine protease
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