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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: AKQMEAALSSK ENYQKVLSEH GFGPITTDIR EGQTFYYAED YHQQYLSKNP NGYCGLGGTG VSCPVGIK
Highest antigen sequence identity to the following orthologs - mouse 87%, rat 65%.
Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. The substrates of MsrA include calmodulin, HIV protease and a 1-proteinase-inhibitor. Recent studies indicate that there is a connection between MsrA and Alzheimer's disease in mammals.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Mitochondrial peptide methionine sulfoxide reductase; Peptide Met(O) reductase; Peptide-methionine (S)-S-oxide reductase; PMSR; Protein-methionine-S-oxide reductase
基因别名: MSRA
Entrez Gene ID: (Human) 4482