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Proteintech
MTA3 Recombinant Rabbit Monoclonal Antibody (230350D12)
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产品信息
83042-3-RR
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
230350D12
抗原
MTA3 fusion protein Ag6400
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: MAANMYRVGD YVYFENSSSN PYLIRRIEEL NKTASGNVEA KVVCFYRRRD ISNTLIMLAD KHAKEIEEES ETTVEADLTD KQKHQLKHRE LFLSRQYESL PATHIRGKCS VALLNETESV LSYLDKEDTF FYSLVYDPSL KTLLADKGEI RVGPRYQADI PEMLLEGESD EREQSKLEVK VWDPNSPLTD RQIDQFLVVA RAVGTFARAL DCSSSVRQPS LHMSAAAASR DITLFHAMDT LYRHSYDLSS AISVLVPLGG PVLCRDEMEE WSASEASLFE EALEKYGKDF NDIRQDFLPW KSLTSIIEYY YMWKTTDRYV QQKRLKAAEA ESKLKQVYIP TYS
靶标信息
Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: metastasis associated gene family, member 3; Metastasis-associated protein MTA3; unnamed protein product
基因别名: 1110002J22Rik; KIAA1266; mKIAA1266; MTA3
UniProt ID: (Human) Q9BTC8, (Mouse) Q924K8
Entrez Gene ID: (Human) 57504, (Mouse) 116871
DNA binding
chromatin binding
transcription coactivator activity
transcription corepressor activity
protein binding
zinc ion binding
histone deacetylase binding
sequence-specific DNA binding
macromolecular complex binding
metal ion binding
transcription factor activity, sequence-specific DNA binding
homeodomain transcription factor
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
chromatin remodeling
regulation of transcription, DNA-templated
cell proliferation
positive regulation of G2/M transition of mitotic cell cycle
regulation of cell fate specification
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of granulosa cell proliferation
granulosa cell proliferation
regulation of stem cell differentiation
positive regulation of cell proliferation
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