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Proteintech
MTF1 Polyclonal Antibody
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产品信息
25383-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Fish,
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MTF1 Fusion Protein Ag21848 (404-753 aa encoded by BC014454)
偶联物
形式
Liquid
浓度
0.24 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: VSDVPPSTG NSASLSLPLV LQPGLSEPPQ PLLPASAPSA PPPAPSLGPG SQQAAFGNPP ALLQPPEVPV PHSTQFAANH QEFLPHPQAP QPIVPGLSVV AGASASAAAV ASAVAAPAPP QSTTEPLPAM VQTLPLGANS VLTNNPTITI TPTPNTAILQ SSLVMGEQNL QWILNGATSS PQNQEQIQQA SKVEKVFFTT AVPVASSPGS SVQQIGLSVP VIIIKQEEAC QCQCACRDSA KERASSRRKG CSSPPPPEPS PQAPDGPSLQ LPAQTFSSAP VPGSSSSTLP SSCEQSRQAE TPSDPQTETL SAMDVSEFLS LQSLDTPSNL IPIEALLQGE EEMGLTSSFS K (404-753 aa encoded by BC014454)
靶标信息
This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Metal regulatory transcription factor 1; metal-regulatory transcription factor 1; metal-responsive transcription factor 1; metalloregulatory transcription factor; MRE-binding transcription factor; MRE-binding transcription factor-1; Transcription factor MTF-1; zinc regulatory factor
基因别名: MTF-1; MTF1; Thyls; ZRF
UniProt ID: (Human) Q14872, (Mouse) Q07243
Entrez Gene ID: (Human) 4520, (Mouse) 17764
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
histone acetyltransferase binding
metal ion binding
nucleic acid binding
C2H2 zinc finger transcription factor
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to oxidative stress
response to metal ion
positive regulation of transcription from RNA polymerase II promoter
response to cadmium ion
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
transition metal ion homeostasis
