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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: KWQEHRRSLE LSSLAGPGED PLSADSLGKP TRVPGGAELS VAAGVAEGQM ENILQEATKE ESGVEEPAHR AGIEIQEGKE DPLLEKESRR KTPEASAIGL HQDPELGDAA LRSHLDMSWP LFSQGISEQQ SGLSVLLSSL QVPPRGEDSL EVPVEQFRIE EIAEGREEAV L
This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-bisphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FYVE domain-containing dual specificity protein phosphatase 1; FYVE-DSP1; Myotubularin-related protein 3; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3; Phosphatidylinositol-3-phosphate phosphatase; Zinc finger FYVE domain-containing protein 10
基因别名: KIAA0371; MTMR3; ZFYVE10
Entrez Gene ID: (Human) 8897