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Sequence of this protein is as follows: MSEPQPRGAE RDLYRDTWVR YLGYANEVGE AFRSLVPAAV VWLSYGVASS YVLADAIDKG KKAGEVPSPE AGRSARVTVA VVDTFVWQAL ASVAIPGFTI NRVCAASLYV LGTATRWPLA VRKWTTTALG LLTIPIIIHP IDRSVDFLLD SSLRKLYPTV GKPSSS
MTP18 (mitochondrial 18 kDa protein), also known as HSPC242, is a 166 amino acid protein essential for cell viability. MTP18 may also have a role in maintaining the integrity of the mitochondrial network. Localized to the mitochonrion, expression of MTP18 is regulated by the PI 3-kinase pathway. Loss of function of MTP18 results in the release of cytochrome c, which subsequently activates the caspase cascade and leads to apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Mitochondrial 18 kDa protein; Mitochondrial fission process protein 1; mitochondrial fission protein MTP18; mitochondrial protein 18 kDa; MTP18
基因别名: HSPC242; MTFP1; MTP18; My022
UniProt ID: (Human) Q9UDX5
Entrez Gene ID: (Human) 51537