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Invitrogen
MTR Polyclonal Antibody
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MTR Antibody (PA5-114366) in IHC (P)
Immunohistochemistry analysis of MTR in paraffin-embedded human pancreatic cancer tissues. Antigen retrieval was performed with citrate buffer (pH6, 20 min). Samples were blocked with 10% goat serum and incubated in MTR polyclonal antibody (Product # PA5-114366) at a dilution of 1 µg/mL (overnight, 4°C), followed by biotinylated goat anti-rabbit IgG (30 min, 37°C) and Strepavidin-Biotin-Complex (SABC) with ... View More
产品信息
PA5-114366
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human MTR recombinant protein (Position: V880-D1095).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human placenta tissue, human K562 whole cell. IHC: human placenta tissue, mouse brain tissue, rat brain tissue, rat brain tissue, human pancreatic cancer tissue. Flow: SiHa cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
MTR encodes the enzyme 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5-methyltetrahydrofolate--homocysteine methyltransferase; 5-methyltetrahydrofolate-homocysteine methyltransferase 1; Cobalamin-dependent methionine synthase; FLJ33168; FLJ43216; FLJ45386; Methionine synthase; MS; Vitamin-B12 dependent methionine synthase
基因别名: AI894170; cblG; D830038K18Rik; HMAG; methioninesynthase; MS; MTR
UniProt ID: (Human) Q99707, (Rat) Q9Z2Q4, (Mouse) A6H5Y3
Entrez Gene ID: (Human) 4548, (Rat) 81522, (Mouse) 238505
sulfur amino acid metabolic process
nervous system development
methionine biosynthetic process
cobalamin metabolic process
axon regeneration
methylation
pteridine-containing compound metabolic process
response to axon injury
cellular response to nitric oxide
protein methylation
methionine metabolic process
tetrahydrofolate metabolic process
homocysteine metabolic process
cellular response to methionine
cellular amino acid biosynthetic process
cellular metabolic process
