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Invitrogen
MYBPC3 Recombinant Rabbit Monoclonal Antibody (19H1L3)
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MYBPC3 Antibody (703574) in WB
Western blot was performed using Anti-MYBPC3 Recombinant Rabbit Monoclonal Antibody (Product # 703574) and a 150 kDa band corresponding to MYBPC3 was observed across the cell lines and tissues tested. Whole cell extracts (30 µg lysate) of iPSC (Lane 1), iPSC differentiated into cardiomyocytes (Lane 2) and tissue extracts of Mouse Heart (Lane 3), Mouse Skeletal Muscle (Lane 4), Rat Heart (Lane 5) and Rat Skeletal Muscle (Lane 6) were electrophoresed using Novex® NuPAGE® 4-12 % Bis-Tris gel (Product # NP0322BOX). Resolved proteins were then ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
703574
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
19H1L3
抗原
Protein corresponding to human MYBPC3 [aa1-aa115]
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.2-7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
This antibody is predicted to react with Bovine.
靶标信息
Myosin binding protein C, cardiac-type (MYBPC3) is a thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments. It modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Mutations affecting the gene can result in cardiomyopathy - familial hypertrophic 4, cardiomyopathy - dilated 1MM, or left ventricular non-compaction 10.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: C-protein, cardiac muscle isoform; cardiac C-protein; Cardiac MyBP-C; DKFZp779E1762; myosin binding protein C, cardiac; Myosin-binding protein C, cardiac-type; sarcomeric protein; unnamed protein product
基因别名: CMD1MM; CMH4; cMyBP-C; FHC; LVNC10; MYBP-C; MYBPC3
UniProt ID: (Rat) P56741
Entrez Gene ID: (Human) 4607, (Rat) 295929, (Mouse) 17868
regulation of heart rate
heart morphogenesis
muscle contraction
regulation of striated muscle contraction
cell adhesion
regulation of heart contraction
myosin filament assembly
sarcomere organization
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
regulation of muscle filament sliding
regulation of cardiac muscle cell contraction
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