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OriGene
MYH Polyclonal Antibody
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产品信息
TA590547
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DNA immunization. This antibody is specific for the C Terminus Region of the target protein.
偶联物
形式
Liquid
浓度
1.26 mg/mL
纯化类型
Protein A/G
保存液
PBS
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cardiac muscle myosin heavy chain 7 beta; MyHC-alpha; MyHC-beta; MyHC-slow; myopathy, distal 1; Myosin heavy chain 6; Myosin heavy chain 7; Myosin heavy chain slow isoform; Myosin heavy chain, cardiac muscle alpha isoform; Myosin heavy chain, cardiac muscle beta isoform; myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1); myosin, heavy polypeptide 7, cardiac muscle, beta; Myosin-6; Myosin-7; rhabdomyosarcoma antigen MU-RMS-40.7A
基因别名: alpha-MHC; ASD3; CMD1EE; CMD1S; CMH1; CMH14; MPD1; MYH6; MYH7; MYHC; MYHCA; MYHCB; SPMD; SPMM; SSS3
UniProt ID: (Human) P13533, (Human) P12883
Entrez Gene ID: (Human) 4624, (Human) 4625
microfilament motor activity
actin binding
calmodulin binding
ATP binding
ATPase activity
myosin phosphatase activity
protein kinase binding
actin-dependent ATPase activity
protein binding
protein homodimerization activity
protein heterodimerization activity
non-receptor serine/threonine protein kinase
in utero embryonic development
regulation of the force of heart contraction
regulation of heart rate
protein dephosphorylation
muscle contraction
striated muscle contraction
adult heart development
visceral muscle development
regulation of heart contraction
regulation of blood pressure
muscle filament sliding
myofibril assembly
BMP signaling pathway
regulation of ATPase activity
sarcomere organization
ATP metabolic process
cardiac muscle fiber development
atrial cardiac muscle tissue morphogenesis
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
canonical Wnt signaling pathway
regulation of heart growth
skeletal muscle contraction
regulation of the force of skeletal muscle contraction
transition between fast and slow fiber
regulation of slow-twitch skeletal muscle fiber contraction
