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产品信息
PA5-64905
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫细胞化学 (ICC/IF) |
0.25-2 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant Human MYO1C |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.05 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.2, with 40% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2661996 |
产品详细信息
Immunogen sequence: GEEETLRRLGL ERNPQSYLYL VKGQCAKVSS INDKSDWKVV RKALTVIDFT EDEVEDLLSI VASVLHLGNI HFAANEESNA QVTTENQLKY LTRLLSVEGS TLREALTHRK IIAKGEELLS PLNLEQAAYA RDALAKAVYS RTFTWLV
Highest antigen sequence identity to the following orthologs - mouse 96%, rat 96%.
靶标信息
MYO1C is a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ23903; MMI-beta; Myosin I beta; myosin-I beta; myosin-Ic; nuclear myosin I; Unconventional myosin-Ic
基因别名: MMI-beta; MMIb; MYO1C; myr2; NMI
UniProt ID: (Human) O00159
Entrez Gene ID: (Human) 4641
分子生物学功能:
actin binding motor protein
protein targeting
protein targeting to membrane
positive regulation of cell migration
positive regulation of cell migration by vascular endothelial growth factor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of gene expression, epigenetic
mRNA transport
positive regulation of protein targeting to membrane
positive regulation of vascular endothelial growth factor signaling pathway
regulation of bicellular tight junction assembly
