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Invitrogen
MYO7A Polyclonal Antibody
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产品信息
PA5-56010
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human MYO7A
偶联物
形式
Liquid
浓度
0.8 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: WAVLTVQAYA RGMIARRLHQ RLRAEYLWRL EAEKMRLAEE EKLRKEMSAK KAKEEAERKH QERLAQLARE DAERELKEKE AARRKKELLE QMERARHEPV NHSDMVDKMF GFLGTSGGLP GQEGQAPSGF E
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
靶标信息
Myosin VIIa is a member of the myosin superfamily of actin-based motor proteins. Defects in the myosin VIIa gene are responsible for hearing impairment in shaker-1 (sh1) mice and causes Usher syndrome IB in humans. Usher syndrome associates congenital deafness, vestibular dysfunction, and retinitis pigmentosa and is the most common form of combined deafness and blindness. Structural features of myosin VIIa protein include an ATP binding N-terminal motor domain, a central region which possess five light-chain binding (IQ) motifs, and a C-terminal domain with three myosin tail homology (MyTH4) and talin-like homology regions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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