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Invitrogen
MYO9B Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-101688
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human MYO9B(Accession Q13459), corresponding to amino acid residues S303-F353.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total MYO9B.
靶标信息
This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: celiac disease 4; myosin; myosin-IXb; myr 5; Unconventional myosin from rat 3; Unconventional myosin-9b; Unconventional myosin-IXb
基因别名: MYO9B; MYR5
Entrez Gene ID: (Mouse) 17925, (Rat) 25486
microfilament motor activity
nucleotide binding
motor activity
actin binding
GTPase activator activity
calmodulin binding
ATP binding
zinc ion binding
ATPase activity
actin-dependent ATPase activity
ATP-dependent protein binding
ADP binding
metal ion binding
actin filament binding
protein binding
protein homodimerization activity
monocyte chemotaxis
signal transduction
Rho protein signal transduction
metabolic process
establishment of cell polarity
actin-myosin filament sliding
intracellular signal transduction
positive regulation of GTPase activity
macrophage chemotaxis
lamellipodium morphogenesis
ARF protein signal transduction
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
