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Invitrogen
MYOM3 Polyclonal Antibody
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MYOM3 Antibody (PA5-100627) in IHC (P)
Immunohistochemistry analysis of MYOM3 in mouse heart tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with MYOM3 polyclonal antibody (Product # PA5-100627) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-100627
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human MYOM3(Accession Q5VTT5), corresponding to amino acid residues N1089-T1139.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total MYOM3.
靶标信息
MYOM3 (myomesin 3) is a structural component of the M-band in striated muscle and is involved in sarcomere stability and resistance during intense or sustained stretching. MYOM3 can be detected mainly in intermediate speed fibers of skeletal muscle. Recently high level of MYOM3 fragments were detected in sera from patients with muscular dystrophy, including Duchenne muscular dystrophy (DMD). MYOM3 fragments may be used as serum biomarker for DMD and other neuromuscular disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Myomesin family member 3; myomesin family, member 3; Myomesin-3
基因别名: 8430427K15Rik; Gm434; MYOM3
UniProt ID: (Human) Q5VTT5, (Mouse) A2ABU4
Entrez Gene ID: (Human) 127294, (Mouse) 242702
