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Invitrogen
MYT1 Polyclonal Antibody
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MYT1 Antibody (PA5-119924) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded human seminal vesicle tissue using MYT1 Polyclonal Antibody (Product # PA5-119924). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the MYT1 antibody at a dilu... View More
产品信息
PA5-119924
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein within human Myt1 aa 900-1121/1121
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
TBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: Hela cell lysate, 293T cell lysate, human seminal vesicle tissue.
Subcellular Location: Nucleus.
靶标信息
The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Myelin transcription factor 1; Myelin transcription factor I; MyT1; MyTI; neural zinc finger transcription factor 2; PLPB1; proteolipid protein binding protein; Proteolipid protein-binding protein
基因别名: C20orf36; KIAA0835; KIAA1050; MTF1; MYT1; MYTI; NZF2; PLPB1; ZC2H2C1; ZC2HC4A
UniProt ID: (Human) Q01538
Entrez Gene ID: (Human) 4661
