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Proteintech
MYT1L Polyclonal Antibody
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产品信息
25234-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MYT1L Fusion Protein Ag18698 (160-473 aa encoded by BC137273)
偶联物
形式
Liquid
浓度
0.51 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: EEEEEEEEN EDHQMNCHNT RIMQDTEKDD NNNDEYDNYD ELVAKSLLNL GKIAEDAAYR ARTESEMNSN TSNSLEDDSD KNENLGRKSE LSLDLDSDVV RETVDSLKLL AQGHGVVLSE NMNDRNYADS MSQQDSRNMN YVMLGKPMNN GLMEKMVEES DEEVCLSSLE CLRNQCFDLA RKLSETNPQE RNPQQNMNIR QHVRPEEDFP GRTPDRNYSD MLNLMRLEEQ LSPRSRVFAS CAKEDGCHER DDDTTSVNSD RSEEVFDMTK GNLTLLEKAI ALETERAKAM REKMAMEAGR RDNMRSYEDQ SPRQL (160-473 aa encoded by BC137273)
靶标信息
MYT1L, myelin transcription factor 1 family, to which the myelin transcription factor 1-like protein (MYT1L) belongs, is expressed primarily in the developing central nervous system and recruits histone deacetylase (HDAC) to regulate neural transcription. Both MYT1L and the related protein MYT1 interact with SIN3B, a protein that mediates transcriptional repression by binding to HDACs, suggesting that the MYT1 family favor the silencing of genes during neural development. Recent studies suggest that polymorphisms of MYT1L may be associated with schizophrenia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Myelin transcription factor 1-like protein; MyT1-L; neural zinc finger transcription factor 1
基因别名: KIAA1106; MRD39; MYT1L; NZF1; ZC2H2C2; ZC2HC4B
UniProt ID: (Human) Q9UL68
Entrez Gene ID: (Human) 23040
