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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
PA3-870 detects Mitofilin from human, mouse, rat, canine, and feline tissues.
PA3-870 has been successfully used in Immunoflorescence, and Western blotting procedures. By Western blot it detects a 90-kDa band representing PA3-870.
PA3-870 antigen is recombinant human Mitofilin.
Mitofilin is a transmembrane protein of the inner mitochondrial membrane and it is associated with a large multimeric protein complex of about 1200 kDa. Mitofilin has critical functions in mitochondrial morphology and mitochondrial fusion and fission, specifically in the formation of tubular cristae and cristae junctions. Abnormal mitochondrial morphology has been implicated in many human diseases such as myopathy, cardiomyopathy, rhabdomyosarcoma and Whartin's tumor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cell proliferation-inducing gene 4/52 protein; cell proliferation-inducing protein 52; heart muscle protein; IMMT; IMMT antibody; inner membrane protein, mitochondrial; inner membrane protein, mitochondrial (mitofilin); inner mitochondrial transmembrane protein; mitochondrial contact site and cristae organizing system subunit 60; mitochondrial inner membrane organizing system 2; mitochondrial inner membrane protein; mitofilin; motor protein; p87/89 antibody; PIG4; PIG52; proliferation-inducing gene 4; unnamed protein product
基因别名: 1700082C19Rik; D830041H16Rik; HMP; Mic60; MICOS60; MINOS2; P87; P87/89; P89; PIG4; PIG52
UniProt ID: (Human) Q16891, (Mouse) Q8CAQ8, (Rat) Q3KR86
Entrez Gene ID: (Human) 10989, (Dog) 475764, (Mouse) 76614, (Rat) 312444