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Invitrogen
Moesin Polyclonal Antibody
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产品信息
PA5-88569
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 458-557 of human Moesin (NP_0024351)
偶联物
形式
Liquid
浓度
1.14 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KTRAELKTAM STPHVAEPAE NEQDEQDENG AEASADLRAD AMAKDRSEEE RTTEAEKNER VQKHLKALTS ELANARDESK KTANDMIHAE NMRLGRDKYK; Positive Samples: HeLa, Jurkat, HepG2, DU145, HT1080, NIH/3T3, Mouse thymus, Mouse lung, Rat lung; Cellular Location: Apical cell membrane, Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cytoskeleton, microvillus membrane
靶标信息
Moesin, a member of the talin-4. 1 superfamily, is a linking protein of the submembraneous actin cytoskeleton. It is expressed in macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. It is involved in cell adhesion, migration, and organization of cell surface structures.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: epididymis luminal protein 70; Membrane-organizing extension spike protein; Moesin
基因别名: C78546; HEL70; MSN
UniProt ID: (Human) P26038, (Rat) O35763, (Mouse) P26041
Entrez Gene ID: (Human) 4478, (Rat) 81521, (Mouse) 17698
movement of cell or subcellular component
cytoskeleton organization
leukocyte cell-cell adhesion
regulation of cell shape
regulation of cell size
positive regulation of gene expression
gland morphogenesis
membrane to membrane docking
establishment of epithelial cell apical/basal polarity
leukocyte migration
establishment of endothelial barrier
cellular response to testosterone stimulus
positive regulation of podosome assembly
regulation of organelle assembly
positive regulation of protein localization to early endosome
positive regulation of cellular protein catabolic process
regulation of lymphocyte migration
positive regulation of early endosome to late endosome transport
