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GenScript
Mosunetuzumab Recombinant Rabbit Monoclonal Antibody (4G6), MonoRab™
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Mosunetuzumab Antibody (A02290-40) in ELISA
Left Figure: Standard Curve of Mosunetuzumab Sandwich ELISA by A02290 (4G6) and A02291 (38A10). In this Sandwich ELISA assay, MonoRab™ Anti-Mosunetuzumab Antibody (4G6), mAb, Rabbit (GenScript, A02290) was coated at a concentration of 1 μg/mL, and MonoRab™ Anti-Mosunetuzumab Antibody (38A10), mAb, Rabbit (GenScript, A02291) conjugated with Biotin was used as a detection antibody at a concentration of 0.4 μg/mL. MRD was as 1:25. In this assay, a four-parameter logistic curve fitting program was used to create a standard curve with the R-Squ... View More
产品信息
A02290-40
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG, kappa
Expression System
Mammalian cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4G6
抗原
Mosunetuzumab
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
Sandwich ELISA recommended dilution: 0.4-2 µg/mL; Competitive ELISA recommended dilution: 1-10 µg/mL
The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles.
靶标信息
Mosunetuzumab is an investigational, humanized, T-cell bispecific antibody designed to engage T cells and redirect their cytotoxic activity against malignant B cells. Mosunetuzumab simultaneously binds to CD3 epsilon (CD3epsilon), a component of the T-cell receptor (TCR) complex, and to CD20, a B-cell surface protein expressed in a majority of B-cell malignancies. This results in crosslinking of the TCR, inducing downstream signaling events that lead to B-cell killing.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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