Description: The monoclonal mouse IgG1 kappa immunoglobulin is useful as an isotype control.
Applications Reported: This P184.108.40.206.1 antibody has been reported for use in flow cytometric analysis.
Our internal testing shows that Alexa Fluor 561 non-specifically stains B cells in Swiss Webster and SJL mice. No non-specific staining has been observed in BALB/c or C57BL/6 mice. Other strains have not been tested. See Antibody Testing Data in the Data Gallery showing this non-specific binding.
Applications Tested: This P220.127.116.11.1 antibody has been tested by flow cytometric analysis of mouse splenocytes and normal human peripheral blood cells and should be used at the same concentration as the experimental antibody.
Alexa Fluor 561 emits at 575 nm and is intended for use on spectral cytometers where it may be multiplexed with both PE and PE-eFluor 610.
Excitation: 558 nm; Emission: 575 nm; Laser: Yellow-Green Laser
Mouse IgG1 is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen. It is the most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response. Mouse IgG1 is composed of two heavy chains and two light chains, and it is involved in opsonization, complement activation, and antibody-dependent cell-mediated cytotoxicity. It is also involved in the regulation of immune responses, including the activation of T cells and the inhibition of B cell activation. Mouse IgG1 is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry. It is also used in therapeutic applications, such as immunotherapy and vaccine development.
蛋白别名: Immunoglobulin G; Immunoglobulin G1; ImmunoglobulinG; ImmunoglobulinG1