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Invitrogen
Moxidectin Recombinant Mouse Monoclonal Antibody (1B2)
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Moxidectin Antibody (MA566408) in SDS-PAGE
SDS-PAGE characterization of Moxidectin under reducing conditions. Lane M: Protein marker (kDa); Lane MXD: Purified Moxidectin Recombinant Monoclonal (Product # MA566408). Moxidectin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-409.
产品信息
MA566408
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1B2
抗原
Conjugate of MXD hapten and KLH.
偶联物
形式
Liquid
浓度
7.5 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Moxidectin is a macrocyclic lactone derived from Streptomyces bacteria, developed in the 1980s by American Cyanamid Co. It is primarily used as an antiparasitic agent in both humans and animals, acting on gamma-aminobutyric acid (GABA) and glutamate-gated channels to induce flaccid paralysis in parasites. Moxidectin is approved for treating human onchocerciasis, a filarial infection prevalent in Africa, Yemen, and parts of South America. In veterinary medicine, it is utilized for controlling heartworm, gastrointestinal nematodes, and lungworms in various animals. Structurally, moxidectin is a milbemycin, distinguishing it from other macrocyclic lactones like avermectins. Its hydrophobic nature contributes to its efficacy and widespread use in pest control. Recent studies have also explored its potential in synergizing with antifungal agents to inhibit Candida albicans biofilm formation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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