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Invitrogen
Muromonab Chimeric Recombinant Mouse Monoclonal Antibody (OKT-3 (muromonab))
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产品信息
MA5-51590
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
OKT-3 (muromonab)
抗原
Human peripheral E+ cells.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.02% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Epitope on the epsilon-subunit within the human CD3 complex.
靶标信息
Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. Muromonab is 93% monomeric immune globulin G type 2a (IgG2a). Muromonab binds to the T-cell surface glycoprotein CD3 epsilon chain. It appears to kill CD-3 positive cells by inducing Fc mediated apoptosis, antibody mediated cytotoxicity and complement-dependent cytotoxicity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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