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Myclobutanil is a systemic triazole fungicide primarily used on grapes and tree fruits, known for its chiral nature with two enantiomers exhibiting different fungicidal activities and toxicological profiles. It functions by inhibiting the biosynthesis of ergosterol, a vital component of fungal cell membranes, thereby disrupting cell growth and replication. Myclobutanil's enantioselective effects have been studied in human models to assess its metabolism and potential risks, highlighting differences in activity and toxicity between its enantiomers. Recent advancements have led to the development of novel nano-formulations, such as carrier-free co-assembled nanoparticles with tannic acid, aimed at enhancing its utilization efficiency. Despite its widespread use, myclobutanil has been associated with adverse effects, including exacerbation of nonalcoholic fatty liver disease, necessitating careful risk assessment and management in agricultural applications.
仅用于科研。不用于诊断过程。未经明确授权不得转售。