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Invitrogen
NAF1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-66821
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: EFNEPGEDFTE VHQNWNAHSS ASEHAKGYRN REFTRGFSRA RYPRSCHGRP PPQHFYNSEH MVSQETSGFP SQRQNNPIMP QYPF
Highest antigen sequence identity to the following orthologs - mouse 69%, rat 73%.
靶标信息
RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: nuclear assembly factor 1 homolog
基因别名: PFBMFT7
UniProt ID: (Human) Q96HR8
Entrez Gene ID: (Human) 92345
snoRNA guided rRNA pseudouridine synthesis
box H/ACA snoRNP assembly
pseudouridine synthesis
ribonucleoprotein complex biogenesis
positive regulation of telomere maintenance via telomerase
ribosome biogenesis
RNA stabilization
telomerase RNA stabilization
telomerase RNA localization to Cajal body
positive regulation of telomere maintenance via telomere lengthening
telomerase holoenzyme complex assembly
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