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Proteintech
NAGS Polyclonal Antibody
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产品信息
21566-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NAGS Fusion Protein Ag16073 (167-534 aa encoded by BC111713)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MDMKPLVVL GLPAPTAPSG CLSFWEAKAQ LAKSCKVLVD ALRHNAAAAV PFFGGGSVLR AAEPAPHASY GGIVSVETDL LQWCLESGSI PILCPIGETA ARRSVLLDSL EVTASLAKAL RPTKIIFLNN TGGLRDSSHK VLSNVNLPAD LDLVCNAEWV STKERQQMRL IVDVLSRLPH HSSAVITAAS TLLTELFSNK GSGTLFKNAE RMLRVRSLDK LDQGRLVDLV NASFGKKLRD DYLASLRPRL HSIYVSEGYN AAAILTMEPV LGGTPYLDKF VVSSSRQGQG SGQMLWECLR RDLQTLFWRS RVTNPINPWY FKHSDGSFSN KQWIFFWFGL ADIRDSYELV NHAKGLPDSF HKPASDPGS (167-534 aa encoded by BC111713)
靶标信息
NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Amino-acid acetyltransferase; amino-acid N-acetyltransferase; MGC133025; N-acetylglutamate synthase, mitochondrial
基因别名: 1700120E20Rik; AGAS; ARGA; NAGS; RGD1565783
UniProt ID: (Human) Q8N159, (Mouse) Q8R4H7
Entrez Gene ID: (Human) 162417, (Rat) 303563, (Mouse) 217214
