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Proteintech
NAGS Recombinant Rabbit Monoclonal Antibody (230279D3), CoraLite® Plus 750
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产品信息
CL750-82963
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
230279D3
抗原
NAGS fusion protein Ag16073
偶联物
激发/发射光谱
755/780 nm
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: MDMKPLVVLG LPAPTAPSGC LSFWEAKAQL AKSCKVLVDA LRHNAAAAVP FFGGGSVLRA AEPAPHASYG GIVSVETDLL QWCLESGSIP ILCPIGETAA RRSVLLDSLE VTASLAKALR PTKIIFLNNT GGLRDSSHKV LSNVNLPADL DLVCNAEWVS TKERQQMRLI VDVLSRLPHH SSAVITAAST LLTELFSNKG SGTLFKNAER MLRVRSLDKL DQGRLVDLVN ASFGKKLRDD YLASLRPRLH SIYVSEGYNA AAILTMEPVL GGTPYLDKFV VSSSRQGQGS GQMLWECLRR DLQTLFWRSR VTNPINPWYF KHSDGSFSNK QWIFFWFGLA DIRDSYELVN HAKGLPDSFH KPASDPGS
靶标信息
NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Amino-acid acetyltransferase; amino-acid N-acetyltransferase; MGC133025; N-acetylglutamate synthase, mitochondrial
基因别名: 1700120E20Rik; AGAS; ARGA; NAGS; RGD1565783
UniProt ID: (Human) Q8N159, (Mouse) Q8R4H7
Entrez Gene ID: (Human) 162417, (Rat) 303563, (Mouse) 217214
