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Proteintech
NAMPT/PBEF Polyclonal Antibody
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产品信息
11776-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat,
Zebrafish
已发表种属
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NAMPT/PBEF Fusion Protein Ag2434 (1-350 aa encoded by BC020691)
偶联物
形式
Liquid
浓度
0.33 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MNPAAEAEF NILLATDSYK VTHYKQYPPN TSKVYSYFEC REKKTENSKL RKVKYEETVF YGLQYILNKY LKGKVVTKEK IQEAKDVYKE HFQDDVFNEK GWNYILEKYD GHLPIEIKAV PEGFVIPRGN VLFTVENTDP ECYWLTNWIE TILVQSWYPI TVATNSREQK KILAKYLLET SGNLDGLEYK LHDFGYRGVS SQETAGIGAS AHLVNFKGTD TVAGLALIKK YYGTKDPVPG YSVPAAEHST ITAWGKDHEK DAFEHIVTQF SSVPVSVVSD SYDIYNACEK IWGEDLRHLI VSRSTQAPLI IRPDSGNPLD TVLKVLEILG KKFPVTENSK GYKLLPPYLR V (1-350 aa encoded by BC020691)
靶标信息
Visfatin, also known as pre-B cell colony-enhancing factor, is an adipocytokine that is abundantly secreted by visceral adipose tissue, with insulin mimetic effects. Visfatin mimics insulin signaling by binding to the insulin receptor and reducing glucose release from liver cells, while stimulating glucose utilization in adipocytes and myocytes. Visfatin is also invoved in enhancement of cell proliferation, biosynthesis of nicotinamide mono-and dinucleotide and glucose homeostasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DKFZp666B131; EC 2.4.2.12; MGC117256; NAmPRTase; nampt; Nicotinamide phosphoribosyltransferase; nicotinamide phosphoribosyltransferase a; PBEF; Pre-B cell-enhancing factor; pre-B-cell colony enhancing factor 1; Pre-B-cell colony-enhancing factor 1; Pre-B-cell colony-enhancing factor 1 homolog; Visfatin
基因别名: 1110035O14Rik; AI314458; AI480535; NAmPRTase; NAMPT; nampta; PBEF; PBEF1; VF; VISFATIN
UniProt ID: (Human) P43490, (Mouse) Q99KQ4, (Rat) Q80Z29
Entrez Gene ID: (Human) 10135, (Mouse) 59027, (Rat) 297508, (Zebrafish) 100330160
nicotinamide metabolic process
signal transduction
cell-cell signaling
female pregnancy
circadian rhythm
positive regulation of cell proliferation
insulin receptor signaling pathway
NAD biosynthetic process
response to organic cyclic compound
circadian regulation of gene expression
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle cell proliferation
positive regulation of nitric-oxide synthase biosynthetic process
adipose tissue development
pyridine nucleotide biosynthetic process
rhythmic process
