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Invitrogen
NCKAP1L Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-58813
产品规格
种属反应
Human
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VLIRMYNIKK TCSDPKSKPP FLLEKSMEPS LKYINKKFPN IDVRNSTQHL GPVHREKAEI IRFLTNYYQS FVD
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 97%.
靶标信息
This gene encodes a member of the HEM family of tissue-specific transmembrane proteins which are highly conserved from invertebrates through mammals. This gene is only expressed in hematopoietic cells. The encoded protein is a part of the Scar/WAVE complex which plays an important role in regulating cell shape in both metazoans and plants. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: hematopoietic protein 1; membrane-associated protein hem-1; unnamed protein product
基因别名: HEM1; IMD72
UniProt ID: (Human) P55160
Entrez Gene ID: (Human) 3071
cell morphogenesis
B cell homeostasis
myeloid cell homeostasis
positive regulation of leukocyte migration
chemotaxis
response to xenobiotic stimulus
cell migration
maintenance of cell polarity
cell projection assembly
positive regulation of actin filament polymerization
cortical actin cytoskeleton organization
positive regulation of B cell proliferation
negative regulation of interleukin-17 production
negative regulation of interleukin-6 production
positive regulation of cell adhesion mediated by integrin
erythrocyte homeostasis
intracellular signal transduction
positive regulation of T cell proliferation
T cell homeostasis
negative regulation of apoptotic process
negative regulation of cytotoxic T cell degranulation
positive regulation of CD4-positive, alpha-beta T cell differentiation
positive regulation of CD8-positive, alpha-beta T cell differentiation
positive regulation of B cell differentiation
positive regulation of gamma-delta T cell differentiation
positive regulation of lymphocyte differentiation
positive regulation of erythrocyte differentiation
neuron projection morphogenesis
erythrocyte development
B cell receptor signaling pathway
positive regulation of phagocytosis, engulfment
protein-containing complex assembly
actin polymerization-dependent cell motility
positive regulation of neutrophil chemotaxis
positive regulation of neutrophil migration
positive regulation of TORC2 signaling
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
