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Invitrogen
NCS1 Polyclonal Antibody
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产品信息
PA1-939
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic Peptide: D(161) G K L T L Q E F Q E G S K A D P S I V Q A L S L Y D G L V(190)
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
PA1-939 detects neuronal calcium sensor-1 (NCS-1) from rat tissues.
PA1-939 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~20 kDa protein representing NCS-1 from rat brain extract.
PA1-939 immunizing peptide corresponds to amino acid residues 161-190 from rat NCS-1. This sequence is completely conserved in mouse, rat, chicken and human NCS-1. There is a single amino acid substitution in this region for Xenopus NCS-1.
靶标信息
This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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