Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
MA5-18029
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500 | - |
酶联免疫吸附实验 (ELISA) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Mouse |
宿主/亚型 |
Armenian hamster / IgG2b |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
N1Nterm1532.8 |
抗原 |
N-terminal peptide of murine Ndfip 1 coupled to KLH (VEPACGSGYQQLQNEEPGE) |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Protein G |
保存液 |
PBS |
内含物 |
0.1% sodium azide |
保存条件 |
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C |
RRID |
AB_2539412 |
产品详细信息
MA5-18029 targets NDFIP1 in ELISA and WB applications and shows reactivity with Mouse samples.
The MA5-18029 immunogen is n-terminal peptide of mouse Ndfip 1 coupled to KLH (VEPACGSGYQQLQNEEPGE).
靶标信息
The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: NEDD4 family-interacting protein 1; Nedd4 WW binding protein 5; NEDD4 WW domain-binding protein 5; Nedd4 WW-binding protein 5
基因别名: 0610010M22Rik; N4wbp5; Ndfip1
UniProt ID: (Mouse) Q8R0W6
Entrez Gene ID: (Mouse) 65113
regulation of myeloid leukocyte differentiation
negative regulation of type 2 immune response
cellular iron ion homeostasis
signal transduction
negative regulation of gene expression
positive regulation of protein ubiquitination
negative regulation of transporter activity
negative regulation of interleukin-4 production
negative regulation of T cell proliferation
positive regulation of I-kappaB kinase/NF-kappaB signaling
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
regulation of lymphocyte differentiation
positive regulation of protein catabolic process
negative regulation of isotype switching to IgE isotypes
regulation of isotype switching to IgG isotypes
negative regulation of inflammatory response
negative regulation of protein transport
