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Invitrogen
NDRG1 Polyclonal Antibody
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产品信息
PA1-27796
产品规格
宿主/亚型
Chicken
/ IgY
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to human N-myc downstream regulated gene 1 variant.
偶联物
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
PA1-27796 detects GC4 from human and mouse samples.
PA1-27796 may be successfully used in Western blot applications. By Western blot, this antibody has only been tested on fusion protein.
The immunogen is a synthetic peptide corresponding to human N-myc downstream regulated gene 1 variant.
靶标信息
NDRG1 is a 394 amino acid cytoplasmic protein belonging to the NDRG family. It interacts with APO A-I and A-II and plays a role in HDL-mediated cholesterol transport, stress responses, hormone responses, cell growth and differentiation. Its defect causes Charcot-Marie-Tooth disease type 4D (CMT4D) that is characterized by reduced nerve conduction velocities, segmental demyelination and remyelination with onion bulb formations on nerve biopsy, slowly progressive distal muscle atrophy and weakness, absent deep tendon reflexes and hollow feet. NDRG1 plays a growth inhibitory role and serves as a marker of differentiation. It is expressed in placental membranes, prostate, kidney, small intestine, ovary tissues, colon and the cells that border the lumen.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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