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产品信息
PA5-114518
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NDST1 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human NDST1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2890335
产品详细信息
Positive controls that may be used include: U937 Cell Lysate
靶标信息
Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L- selectin ligands, thereby playing a role in inflammatory response.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: [Heparan sulfate]-glucosamine N-sulfotransferase 1; Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1; Glucosaminyl N-deacetylase/N-sulfotransferase 1; heparan sulfate-N-deacetylase/N-sulfotransferase; heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase 1; HSNST 1; N-Deacetylase-N-sulfotransferase 1; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1; N-deacetylase/N-sulfotransferase 1; N-heparan sulfate sulfotransferase 1; N-HSST 1; NDST-1
基因别名: HSST; HSST1; MRT46; NDST1; NST1
UniProt ID: (Human) P52848
Entrez Gene ID: (Human) 3340
MAPK cascade
polysaccharide biosynthetic process
cardiac septum development
glycosaminoglycan biosynthetic process
protein sulfation
inflammatory response
smoothened signaling pathway
respiratory gaseous exchange
fibroblast growth factor receptor signaling pathway
heparan sulfate proteoglycan biosynthetic process
heparin biosynthetic process
forebrain development
midbrain development
aorta development
embryonic neurocranium morphogenesis
embryonic viscerocranium morphogenesis
coronary vasculature development
