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Invitrogen
NDUFS2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-19342
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse,
Non-human primate
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (SRGVRQWQPDVE) corresponding to the internal amino acids of NDUFS2 (aa 31-42).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with bovine, canine, porcine and rabbit based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
靶标信息
The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase. Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CI-49kD; comp; Complex I-49kD; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; NADH-coenzyme Q reductase; NADH-ubiquinone oxidoreductase 49 kDa subunit; ndufs2 {ECO:0000312|EMBL:AAH82067.1}
基因别名: AL033311; Ndufs2
UniProt ID: (Mouse) Q91WD5, (Rat) Q641Y2
Entrez Gene ID: (Mouse) 226646, (Rat) 289218
NADH dehydrogenase activity
NADH dehydrogenase (ubiquinone) activity
oxidoreductase activity
oxidoreductase activity, acting on NAD(P)H
ubiquitin protein ligase binding
metal ion binding
quinone binding
NAD binding
iron-sulfur cluster binding
4 iron, 4 sulfur cluster binding
molecular_function
oxidoreductase
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