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NEK11 (FLJ23495) belongs to the NIMA family of kinases which are involved in DNA replication and genotoxic stress response. NEK11 encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Never in mitosis A-related kinase 11; NIMA (never in mitosis gene a)- related kinase 11; NimA-related protein kinase 11; Serine/threonine-protein kinase Nek11
基因别名: NEK11
UniProt ID: (Human) Q8NG66
Entrez Gene ID: (Human) 79858