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Invitrogen
NFE4 Polyclonal Antibody
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NFE4 Antibody (PA5-116358) in WB
Western Blot analysis of NFE4 using the NFE4 Polyclonal Antibody (Product # PA5-116358) at a 1:2000 dilution. Lane 1: K562 whole cell lysates, Lane 2: 293T/17 whole cell lysates, Lane 3: human kidney lysates, Lane 4: human spleen lysates. Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10,000 dilution Predicted band size : 19 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
产品信息
PA5-116358
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 102-136 amino acids from the Central region of human NFE4
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Functions as part of the SSP (stage selector protein) complex, a complex that contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR). The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter. In contrast, isoform 2 acts as a repressor of gamma- globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: fetal globin activator NF-E4; gamma-globin gene activator
基因别名: NF-E4
Entrez Gene ID: (Human) 58160
