Invitrogen

NFIL3 Polyclonal Antibody

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NFIL3 Antibody in Western Blot (WB) — Western blot analysis of NFIL3 by a NFIL3 monoclonal antibody (Product # PA5-17978) at a concentration of 1 µg/mL. Jurkat nuclear cell lysate (RIPA buffer, 20µg total protein per lane). Detected using chemiluminescence.

NFIL3 Antibody in Flow Cytometry (Flow) — Flow cytometric analysis of NFIL3 in Human peripheral blood mononuclear cells using a polyclonal antibody (Product #PA5-17978). Human peripheral blood mononuclear cells (blue line) were paraformaldehyde fixed and permeabilized with 0.5% Triton. The primary antibody was incubated for one hour (10 µg/mL) followed by an Alexa Fluor 488 secondary antibody (2 µg/mL). IgG control: Unimmunized goat IgG (black line) followed by an Alexa Fluor 488 secondary antibody.

产品信息

PA5-17978

应用	建议稀释比	已发表文章
免疫印迹 (WB)	0.5-2 µg/mL	-
流式细胞分析 (Flow)	Assay-dependent	-

产品规格
种属反应	Human
宿主/亚型	Goat / IgG
分类	Polyclonal
类型	Antibody
抗原	Synthetic peptide sequence (RLIATQPISASDSG) corresponding to the C-terminus amino acids of NFIL3
偶联物	Unconjugated
形式	Liquid
浓度	0.5 mg/mL
纯化类型	Antigen affinity chromatography
保存液	TBS, pH 7.3, with 0.5% BSA
内含物	0.02% sodium azide
保存条件	-20° C, Avoid Freeze/Thaw Cycles
RRID	AB_10989299

产品详细信息

This antibody is predicted to react with mouse and rat based on sequence homology.

靶标信息

Expression of interleukin-3 (IL3; MIM 147740) is restricted to activated T cells, natural killer (NK) cells, and mast cell lines. Transcription initiation depends on the activating capacity of specific protein factors, such as NFIL3, that bind to regulatory regions of the gene, usually upstream of the transcription start site (Zhang et al., 1995 [PubMed 7565758]).

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: E4 promoter-binding protein 4; Interleukin-3 promoter transcriptional activator; Interleukin-3-binding protein 1; NF IL3A; nuclear factor interleukin 3 regulated protein; Nuclear factor interleukin-3-regulated protein; OTTHUMP00000021633; Transcriptional activator NF-IL3A

基因别名: E4BP4; IL3BP1; NF-IL3A; NFIL3; NFIL3A

UniProt ID: (Human) Q16649

Entrez Gene ID: (Human) 4783

分子生物学功能: basic leucine zipper transcription factor DNA-binding transcription factor gene-specific transcriptional regulator

功能

negative regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter immune response circadian rhythm positive regulation of gene expression cellular response to interleukin-4

参与通路

RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding transcription corepressor activity protein binding

NFIL3 Polyclonal Antibody

产品信息

PA5-17978

免疫印迹 (WB)

流式细胞分析 (Flow)

种属反应

宿主/亚型

分类

类型

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

RRID

产品详细信息

靶标信息

篇参考文献 (0)

生物信息学

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