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Abnova
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Immunogen sequence: FPEDSAEQQN ELILALFSGE NFRFGNPLHI AQKLFRDGHF NPEVVKYRQL CFKSQYKRYL NSQQQYFHRL LKQILASRSD LLEMARRSGP ALPFRQKRPS PSRTPEER
NFRKB (nuclear factor related to kappa-B-binding protein) was first identified as a factor that could bind a variant NF-kappa B site in the interleukin-2 receptor alpha (IL-2R alpha) gene. NFRKB appears to be a transcription factor central to immune cell development. Evidence of this comes from the identification of NFRKB as an amplified gene in several cases of acute myeloid leukemia. Additionally, in another clinical case, a partial deletion of the chromosomal region that includes NFRKB is shown to be associated with combined cellular immunodeficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DNA-binding protein R kappa B; DNA-binding protein R kappa-B; INO80 complex subunit G; Nuclear factor related to kappa-B-binding protein
基因别名: INO80G; NFRKB
UniProt ID: (Human) Q6P4R8
Entrez Gene ID: (Human) 4798