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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: PAAAFRSPLA RQLFRIEGVK SVFFGPDFIT VTKENEELDW NLLKPDIYAT IMDFFASGLP LVTEETPSGE AGSEEDD
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 99%.
This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HIRA-interacting protein 5; iron-sulfur cluster scaffold protein; NifU-like C-terminal domain containing; unnamed protein product
基因别名: CGI-33; HIRIP; HIRIP5; MMDFS; MMDS1; Nfu; NifU; NIFUC; SPG93
UniProt ID: (Human) Q9UMS0
Entrez Gene ID: (Human) 27247