Proteintech

NFX1 Polyclonal Antibody

Name: NFX1 Polyclonal Antibody
Brand: Proteintech
SKU: 16387-1-AP

查看其他8个NFX1抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)

图: 1 / 2

NFX1 Antibody (16387-1-AP) in WB

K-562 cells were subjected to SDS PAGE followed by western blot with 16387-1-AP (NFX1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Immunogen image

Immunogen Image NFX1 Polyclonal Antibody

产品信息

16387-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2400

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

NFX1 Fusion Protein Ag9448 (771-1120 aa encoded by BC012151)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.13 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: TCARVHECD HPVYHSCHSE EKCPPCTFLT QKWCMGKHEF RSNIPCHLVD ISCGLPCSAT LPCGMHKCQR LCHKGECLVD EPCKQPCTTP RADCGHPCMA PCHTSSPCPV TACKAKVELQ CECGRRKEMV ICSEASSTYQ RIAAISMASK ITDMQLGGSV EISKLITKKE VHQARLECDE ECSALERKKR LAEAFHISED SDPFNIRSSG SKFSDSLKED ARKDLKFVSD VEKEMETLVE AVNKGKNSKK SHSFPPMNRD HRRIIHDLAQ VYGLESVSYD SEPKRNVVVT AIRGKSVCPP TTLTGVLERE MQARPPPPIP HHRHQSDKNP GSSNLQKITK EPIIDYFDVQ D (771-1120 aa encoded by BC012151)

靶标信息

MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma.MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: DKFZp779G2416; m-Nfx.1; MGC20369; Nuclear transcription factor, X box-binding protein 1; testis expressed gene 42; Transcriptional repressor NF-X1; X-box binding 1

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基因别名: 1300017N15Rik; 3000003M19Rik; NFX.1; NFX1; NFX2; TEG-42; Tex42

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UniProt ID: (Human) Q12986, (Mouse) B1AY10

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Entrez Gene ID: (Human) 4799, (Rat) 313166, (Mouse) 74164

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