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Invitrogen
NKAP Polyclonal Antibody
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NKAP Antibody (PA5-78578) in ICC/IF
NKAP Polyclonal Antibody detects NKAP protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde/PBS for 15 min. Green: NKAP protein stained by NKAP Polyclonal Antibody (Product # PA5-78578) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-78578
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the C-terminus region of human NKAP. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Predicted Reactivity: Mouse (98%), Rat (97%), Zebrafish (82%), Xenopus laevis (85%), Pig (97%), Chicken (91%), Rhesus Monkey (100%), Bovine (97%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
NKAP is a transcriptional repressor that associates with the NOTCH (see MIM 190198) corepressor complex and is required for T-cell development.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ22626; NF-kappa-B-activating protein; NF-kappaB activating protein
基因别名: NKAP
UniProt ID: (Human) Q8N5F7
Entrez Gene ID: (Human) 79576
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
Notch signaling pathway
stem cell population maintenance
granulocyte differentiation
T cell differentiation in thymus
negative regulation of transcription, DNA-templated
positive regulation of alpha-beta T cell differentiation
hematopoietic stem cell proliferation
positive regulation of protein targeting to mitochondrion
