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Natural killer (NK) cells are lymphocytes that can mediate the lysis of certain tumor cells and virus infected cells without being previously activated. They can also regulate specific humoral and cell mediated immunity. NK cells preferentially express several calcium dependent (C type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C type lectin genes preferentially expressed on NK cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C-lectin type II protein; CD159 antigen-like family member A; CD159 antigen-like family member C; CD159a; CD159c; killer cell lectin-like receptor subfamily C, member 1; killer cell lectin-like receptor subfamily C, member 2; killer cell lectin-like receptor subfamily C, member 3; killer cell lectin-like receptor subfamily C, member 4; natual killer cell group 2-F; natural killer cell lectin; natural killer group protein 2; NK cell receptor A; NK cell receptor C; NK cell receptor E; NK cell receptor F; NKG2-1/B activating NK receptor; NKG2-A/B type II integral membrane protein; NKG2-A/B-activating NK receptor; NKG2-A/NKG2-B type II integral membrane protein; NKG2-C type II integral membrane protein; NKG2-C-activating NK receptor; NKG2-E type II integral membrane protein; NKG2-E-activating NK receptor; NKG2-F type II integral membrane protein; NKG2-F-activating NK receptor
基因别名: CD159A; CD159c; KLRC1; KLRC2; KLRC3; KLRC4; NKG2; NKG2-C; NKG2-E; NKG2-F; NKG2A; NKG2C; NKG2E; NKG2F
UniProt ID: (Human) P26715, (Human) P26717, (Human) Q07444, (Human) O43908
Entrez Gene ID: (Human) 3821, (Human) 3822, (Human) 3823, (Human) 8302