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Invitrogen
NMBR Polyclonal Antibody
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NMBR Antibody (PA5-78080) in WB
Western Blot using NMBR Polyclonal Antibody (Product # PA5-78080). Untreated (–) and treated (+) HeLa whole cell extracts (30 µg) were separated by 10% SDS-PAGE, and the membrane was blotted with NMBR Polyclonal Antibody (Product # PA5-78080) diluted at 1:1,000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
产品信息
PA5-78080
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the C-terminus region of Human NMBR. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: HeLa, HeLa (500 µM CoCl2 treatment for 24 hr)
Predicted Reactivity: Mouse (88%), Rat (88%), Pig (85%), Rhesus Monkey (96%), Bovine (93%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
NMBR, also known as neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues. Neuromedin B receptor expression has been reported in brain, particularly the olfactory bulb and thalamus, and in colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. In addition, it has been shown to be present in cancer of the lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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