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产品信息
PA5-65852
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human NME7
偶联物
Unconjugated
形式
Liquid
浓度
0.6 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2665260
产品详细信息
Immunogen sequence: SIRALFGTDGI RNAAHGPDSF ASAAREMELF FPSSGGCGPA NTAKFTNCTC CIVKPHAVSE GLLGKILMAI RDAGFEISAM QMFNMDRVN
Highest antigen sequence identity to the following orthologs - mouse 87%, rat 88%.
靶标信息
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
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生物信息学
蛋白别名: cilia and flagella associated protein 67; NDK 7; NDP kinase 7; nm23-H7; non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase); Nucleoside diphosphate kinase 7; nucleoside-diphosphate kinase 7
基因别名: CFAP67; MN23H7; NDK 7; NDK7; nm23-H7; NME7
UniProt ID: (Human) Q9Y5B8
Entrez Gene ID: (Human) 29922
分子生物学功能:
kinase
transferase
metabolite interconversion enzyme
