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Invitrogen
NOD2 Polyclonal Antibody
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产品信息
PA5-111394
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Protein corresonding to Human NOD2
偶联物
形式
Liquid
浓度
0.10 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: PGNSPMARLL PTMCIQASEG KDSSVAALLQ KAEPHNLQIT AAFLAGLLSR EHWGLLAECQ TSEKALLRRQ ACARWCLARS LRKHFHSIP
靶标信息
NOD2 is a member of the apoptosis regulating protein family that includes caspase recruitment-domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs). NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues). NOD2 plays a role in regulating NF-kappaB, acts as an intracellular receptor for bacterial lipopolysaccharides, and contributes to inflammatory bowel disease (IBD) and Crohn's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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