FIGURE: 1 / 6
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.
Protein Aliases: Neuro-oncological ventral antigen 1; Onconeural ventral antigen 1; Paraneoplastic Ri antigen; RNA-binding protein Nova-1; Ventral neuron-specific protein 1
Gene Aliases: 9430099M15Rik; G630039L02; Nova-1; NOVA1
Molecular Function: RNA metabolism protein